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4.1.1.B12: lysine/ornithine carboxy-lyase

This is an abbreviated version!
For detailed information about lysine/ornithine carboxy-lyase, go to the full flat file.

Word Map on EC 4.1.1.B12

Reaction

L-lysine
=
cadaverine
+
CO2

Synonyms

arginine/ornithine decarboxylase, HsLDC, L-lysine decarboxylase, L/ODC, LcL/ODC, LDC, LDC/ODC, Lys/Orn decarboxylase, lysine/ornithine decarboxylase, More, OAD, OAD1, SrLDC, vvLDC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.B12 lysine/ornithine carboxy-lyase

pH Range

pH Range on EC 4.1.1.B12 - lysine/ornithine carboxy-lyase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
8 - 10
-
50% of maximal activity at pH 8.0 and pH 10.0, maximal activity at pH 9.0, conversion rate at pH 9.0 is 40%
8 - 9
enzyme srLDC does not exhibit effective activity in alkaline pH conditions, the conversion rate of about 25% is similar at pH 8.0 and pH 9.0, no activity at pH 10.0
additional information
-
enzyme vvLDC exhibits effective activity in alkaline pH conditions