4.1.1.B12: lysine/ornithine carboxy-lyase
This is an abbreviated version!
For detailed information about lysine/ornithine carboxy-lyase, go to the full flat file.
Word Map on EC 4.1.1.B12
Reaction
Synonyms
arginine/ornithine decarboxylase, HsLDC, L-lysine decarboxylase, L/ODC, LcL/ODC, LDC, LDC/ODC, Lys/Orn decarboxylase, lysine/ornithine decarboxylase, More, OAD, OAD1, SrLDC, vvLDC
ECTree
4.1.1.B12 lysine/ornithine carboxy-lyaseAdvanced search results
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Substrates Products on EC 4.1.1.B12 - lysine/ornithine carboxy-lyase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-lysine
cadaverine + CO2
-
3.0% cataytic efficiency compared to L-lysine
-
-
?
L-arginine
agmatine + CO2
-
19.5% cataytic efficiency compared to L-lysine
-
-
?
L-methionine
3-(methylsulfanyl)propanamine + CO2
-
21.0% cataytic efficiency compared to L-lysine
-
-
?
L-phenylalanine
phenylethylamine + CO2
-
1.2% cataytic efficiency compared to L-lysine
-
-
?
L-valine
2-methylpropanamine + CO2
-
1.8% cataytic efficiency compared to L-lysine
-
-
?
additional information
?
-
-
substrate specificity, overview. No activity with 2,3-diaminopropionic acid, 2,4-diaminobutric acid, and 2,7-diaminoheptanoic acid
-
-
?
L-lysine
cadaverine + CO2
the ratio of catalytic efficiency with L-Lys to efficiency with L-Orn is 1.03
-
-
?
L-lysine
cadaverine + CO2
the ratio of catalytic efficiency with L-Lys to efficiency with L-Orn is 0.5 in wild type
-
-
?
L-lysine
cadaverine + CO2
the ratio of catalytic efficiency with L-Lys to efficiency with L-Orn is 1.47
-
-
?
L-ornithine
putrescine + CO2
the ratio of catalytic efficiency with L-Lys to efficiency with L-Orn is 1.03
-
-
?
L-ornithine
putrescine + CO2
-
92% cataytic efficiency compared to L-lysine
-
-
?
L-ornithine
putrescine + CO2
the ratio of catalytic efficiency with L-Lys to efficiency with L-Orn is 0.5 in wild type
-
-
?
L-ornithine
putrescine + CO2
the ratio of catalytic efficiency with L-Lys to efficiency with L-Orn is 1.47
-
-
?
