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4.1.1.17: ornithine decarboxylase

This is an abbreviated version!
For detailed information about ornithine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.17

Reaction

L-ornithine
=
putrescine
 +
CO2

Synonyms

AdoMetDC/ODC, BN36_1212510, bODC, DDB_G0281109, DdODC, Decarboxylase, ornithine, dODC, LDC/ODC, LdODC, lysine/ornithine decarboxylase, ODC, ODC-paralogue, ODC1, ornithine decarboxylase, PfAdoMetDC-ODC, PfODC/AdoMetDC, S-adenosylmethionine decarboxylase/ornithine decarboxylase, SpeC, XODC1, XODC2, YODC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.17 ornithine decarboxylase

KI Value

KI Value on EC 4.1.1.17 - ornithine decarboxylase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00046
(2S)-5-amino-2-hydrazinylpentanoic acid
-
-
0.000001
1-amino-oxy-3-aminopropane
0.0271
1H-indol-3-yl(morpholin-4-yl)acetonitrile
at pH 7.5 and 37°C
0.1
2-phenylethyl carbamimidothioate
Ki above 0.1 mM, at pH 7.5 and 37°C
0.1
3-(morpholin-4-ylmethyl)-1H-indole
Ki above 0.1 mM, at pH 7.5 and 37°C
0.0289
4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide
at pH 7.5 and 37°C
0.0027
alexidine
at pH 7.5 and 37°C
0.026 - 0.088
alpha-difluoromethylornithine
0.09
alpha-difluoroornithine
-
recombinant Pf-Hinge-ODC
0.8
Ba2+
-
-
0.0036
benzene-1,3-diyldiethane-2,1-diyl dicarbamimidothioate
at pH 7.5 and 37°C
0.1
benzene-1,4-diyldimethanediyl dicarbamimidothioate
Ki above 0.1 mM, at pH 7.5 and 37°C
0.1
but-2-yne-1,4-diyl dicarbamimidothioate
Ki above 0.1 mM, at pH 7.5 and 37°C
0.0288
butane-1,4-diyl dicarbamimidothioate
at pH 7.5 and 37°C
0.9
Ca2+
-
-
0.00002
CGP52622A
-
-
0.000008
CGP54619A
-
-
-
0.5
Co2+
-
-
0.38
D-ornithine
-
pH 7.8, 25°C
4.5 - 8
geneticin
220
K+
-
-
15
Mg2+
-
-
1
Mn2+
-
-
0.1
N-(4-ethoxy-1,3-benzothiazol-2-yl)-4-methoxybenzamide
Ki above 0.1 mM, at pH 7.5 and 37°C
0.014
N-(4-ethoxy-1,3-benzothiazol-2-yl)-4-propoxybenzamide
at pH 7.5 and 37°C
0.1
N-(4-ethoxy-1,3-benzothiazol-2-yl)benzamide
Ki above 0.1 mM, at pH 7.5 and 37°C
0.1
N-(6-ethoxy-1,3-benzothiazol-2-yl)-4-propoxybenzamide
Ki above 0.1 mM, at pH 7.5 and 37°C
300
Na+
-
-
0.0102
pentane-1,5-diyl dicarbamimidothioate
at pH 7.5 and 37°C
0.016
Phaseolotoxin
-
pH 7.3, 37°C
0.1
propane-1,3-diyl dicarbamimidothioate
Ki above 0.1 mM, at pH 7.5 and 37°C
0.05 - 0.25
putrescine
0.8
Zn2+
-
-