3.6.1.55: 8-oxo-dGTP diphosphatase

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For detailed information about 8-oxo-dGTP diphosphatase, go to the full flat file.

Reaction

Synonyms

7,8-dihydro-8-oxo-dGTP pyrophosphohydrolase, 8-oxo-2'-deoxyguanosine triphosphatase, 8-oxo-dG triphosphatase, 8-oxo-dGTP diphosphatase, 8-oxo-dGTP hydrolase, 8-oxo-dGTPase, AK369000, CiMutT, MTH1, MuT, MutT, MutT homolog 1, MutT homologue 1, MutT2, Nudix hydrolase, NUDT1, Nudx12

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.55 8-oxo-dGTP diphosphatase

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Results	in table
3965	AA Sequence
8	Cloned(Commentary)
4	Crystallization (Commentary)
210	Disease/ Diagnostics
3	Expression
6	General Information
11	IC50 Value
17	Inhibitors
2	kcat/KM [mM/s]
16	Ki Value [mM]
12	KM Value [mM]
7	Metals/Ions
2	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
21	Organism
1	Pathway
189	PDB ID
6	pH Optimum
1	pH Range
5	Purification (Commentary)
1	Reaction
21	Reference
4	Source Tissue
2	Specific Activity [micromol/min/mg]
68	Substrates and Products (Substrate)
1	Subunits
33	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
2	Turnover Number [1/s]

Expression

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Expression on EC 3.6.1.55 - 8-oxo-dGTP diphosphatase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

expression is upregulated by drought and UV-C stress

Hordeum vulgare subsp. vulgare

F2DYN1

733536

MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure

2 entries

MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure

Escherichia coli

-

716300

MutT molecules are needed for keeping the spontaneous mutation frequency at the normal level. The MutT functions are not needed under anaerobic condition, yet the level of the MutT protein in cell is kept constant, probably for preparing for sudden changes of oxygen pressure

Escherichia coli CC101

-

-