3.6.1.45: UDP-sugar diphosphatase

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For detailed information about UDP-sugar diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.45

3.6.1.45

cholera

clostridium

difficile

retrograde

mucosal

diarrhea

iga

rho

gm1

tracer

tcda

ganglioside

stool

toxigenic

colitis

innervation

afferent

gtpases

anterograde

intranasal

tracing

difficile-associated

nosocomial

cdc42

cytotoxin

botulinum

pseudomembranous

antibiotic-associated

rostral

enterotoxin

sordellii

cytolethal

toxoid

intermediolateral

clostridioides

parabrachial

parvicellular

leucoagglutinin

antibody-secreting

ventrolateral

enterotoxigenic

transganglionic

antitoxin

ribotype

pentameric

tract-tracing

fluoro-gold

holotoxin

non-toxigenic

preganglionic

Reaction

Synonyms

5'-nucleotidase/UDP-sugar hydrolase, hydrolase, uridine diphosphoglucose (Escherichia coli precursor reduced), hydrolase, uridine diphosphoglucose (Escherichia coli reduced), hydrolase, uridine diphosphoglucose (Salmonella typhimurium clone pAGS5 gene ushB isoenzyme reduced), hydrolase, uridine diphosphoglucose (Salmonella typhimurium gene ushA0 isoenzyme precursor reduced), hydrolase, uridine diphosphoglucose (Salmonella typhimurium gene ushA0 isoenzyme reduced), nucleosidediphosphate-sugar diphosphatase, nucleosidediphosphate-sugar pyrophosphatase, Nudix hydrolase-like nucleotide hydrolase, toxin A, toxin B, UDP-glucose pyrophosphatase, UDP-sugar diphosphatase, UDP-sugar hydrolase, UDP-sugar pyrophosphatase, UDPG pyrophosphatase, UGPPase, UshA, UshB protein

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.45 UDP-sugar diphosphatase

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Results	in table
1361	AA Sequence
8	CAS Registry Number
11	Cloned(Commentary)
4838	Disease/ Diagnostics
2	General Information
13	Inhibitors
4	kcat/KM [mM/s]
26	KM Value [mM]
12	Localization
11	Metals/Ions
14	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
31	Organism
47	PDB ID
7	pH Optimum
2	pH Range
1	pI Value
6	Protein Variants
8	Purification (Commentary)
3	Reaction
3	Reaction Type
30	Reference
12	Source Tissue
6	Specific Activity [micromol/min/mg]
43	Substrates and Products (Substrate)
13	Subunits
35	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 3.6.1.45 - UDP-sugar diphosphatase

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UDP-sugar sugarphosphohydrolase

A divalent cation is required for activity. UDP-sugar is the best substrate, although other nucleoside-sugar diphosphates are used as substrates with similar Km values but much lower maximum velocities. Thus, this enzyme has a specificity distinct from that of ADP-sugar diphosphatase (EC 3.6.1.21). Some but not all enzymes of this class also appear to have 5'-nucleotidase (see EC 3.1.3.5) activity.