3.5.1.B15: pyrazinamidase
This is an abbreviated version!
For detailed information about pyrazinamidase, go to the full flat file.
Word Map on EC 3.5.1.B15
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3.5.1.B15
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tuberculosis
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mycobacterium
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pzase
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pyrazinoic
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pza-resistant
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bactec
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pyrazinamide-resistant
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enterocolitica
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wayne
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mdr-tb
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middlebrooks
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autoagglutination
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pza-susceptible
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kristensenii
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kansasii
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diagnostics
- 3.5.1.B15
- tuberculosis
- mycobacterium
- pzase
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pyrazinoic
-
pza-resistant
-
bactec
-
pyrazinamide-resistant
- enterocolitica
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wayne
-
mdr-tb
-
middlebrooks
-
autoagglutination
-
pza-susceptible
- kristensenii
- kansasii
- diagnostics
Reaction
Synonyms
ASAC_0847, BsPncA, More, nicotinamidase/pyrazinamidase, PH0999, PncA, PolyNic, pyrazinamidase, pyrazinamidase/nicotinamidase, PZAase, PZAse
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Application on EC 3.5.1.B15 - pyrazinamidase
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APPLICATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
diagnostics
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the pyrazinamidase activity in pyrazinamide (PZA)-resistant isolates is an important parameter to determine the susceptibility to pyrazinoic acid (PZA) because PZase converts PZA into pyrazinoic acid, which is protonated and becomes active against the mycobacterium. A nonfunctional PZase allows the mycobacterium to survive in the presence of PZA
