3.5.1.B15: pyrazinamidase
This is an abbreviated version!
For detailed information about pyrazinamidase, go to the full flat file.
Word Map on EC 3.5.1.B15
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3.5.1.B15
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tuberculosis
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mycobacterium
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pzase
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pyrazinoic
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pza-resistant
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bactec
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pyrazinamide-resistant
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enterocolitica
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wayne
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mdr-tb
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middlebrooks
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autoagglutination
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pza-susceptible
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kristensenii
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kansasii
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diagnostics
- 3.5.1.B15
- tuberculosis
- mycobacterium
- pzase
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pyrazinoic
-
pza-resistant
-
bactec
-
pyrazinamide-resistant
- enterocolitica
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wayne
-
mdr-tb
-
middlebrooks
-
autoagglutination
-
pza-susceptible
- kristensenii
- kansasii
- diagnostics
Reaction
Synonyms
ASAC_0847, BsPncA, More, nicotinamidase/pyrazinamidase, PH0999, PncA, PolyNic, pyrazinamidase, pyrazinamidase/nicotinamidase, PZAase, PZAse
ECTree
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Activating Compound
Activating Compound on EC 3.5.1.B15 - pyrazinamidase
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glycerol
increases the enzyme activity up to 130% at 37°C, gives rise to an increase in the content of alpha-helix and beta-sheets elements. More stability of PZase in glycerol solution correlates with its amphiphilic orientation, which decreases the unfavorable interactions of hydrophobic regions.
sorbitol
increases the enzyme activity up to 110% at 37°C, gives rise to an increase in the content of alpha-helix and beta-sheets elements