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3.4.23.38: plasmepsin I

This is an abbreviated version!
For detailed information about plasmepsin I, go to the full flat file.

Word Map on EC 3.4.23.38

Reaction

hydrolysis of the -Phe33-/-Leu- bond in the alpha-chain of hemoglobin, leading to denaturation of the molecule =

Synonyms

AH I, aspartic hemoglobinase I, malaria aspartic hemoglobinase, PFAPG, PfPM1, plasmepsin 1, plasmepsin I, plasmepsin-I, PLm I, PM I, PM-I, PMI

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.38 plasmepsin I

Natural Substrates Products

Natural Substrates Products on EC 3.4.23.38 - plasmepsin I

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Hemoglobin + H2O
?
show the reaction diagram
additional information
?
-
-
plasmepsin I is synthesized and processed to the mature form soon after the parasite invades the red blood cell
-
-
?