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3.4.22.B66: caspase-12

This is an abbreviated version!
For detailed information about caspase-12, go to the full flat file.

Word Map on EC 3.4.22.B66

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Synonyms

Casp12, caspase-12

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B66 caspase-12

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Resultsin table
1Activating Compound
3AA Sequence
1Application
551Disease/ Diagnostics
2Expression
11General Information
3Localization
2Molecular Weight [Da]
12Organism
1Protein Variants
12Reference
12Source Tissue
2Subunits
4Synonyms

Application

Application on EC 3.4.22.B66 - caspase-12

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
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endoplasmic reticulum stress may be associated with apoptosis of lens epithelial cells, resulting in cataract formation in diabetic patients. The expression of calpain and caspase-12 is in highest diabetic cataract patients with proliferative diabetic retinopathy, followed by diabetic cataract patients with nonprolifeative diabetic retinopathy, cataract patients with diabetes mellitus and without diabetic retinopathy, and finally cataract patients without diabetes mellitus