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Literature summary for 3.4.22.B66 extracted from
- Calpain and caspase-12 expression in lens epithelial cells of diabetic cataracts (2016), Am. J. Ophthalmol., 167, 31-37 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | endoplasmic reticulum stress may be associated with apoptosis of lens epithelial cells, resulting in cataract formation in diabetic patients. The expression of calpain and caspase-12 is in highest diabetic cataract patients with proliferative diabetic retinopathy, followed by diabetic cataract patients with nonprolifeative diabetic retinopathy, cataract patients with diabetes mellitus and without diabetic retinopathy, and finally cataract patients without diabetes mellitus | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lens epithelium | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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