3.4.22.B30: calpain 10
This is an abbreviated version!
For detailed information about calpain 10, go to the full flat file.
Word Map on EC 3.4.22.B30
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3.4.22.B30
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calpains
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mellitus
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ucsnp-43
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polycystic
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tcf7l2
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mexican
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kcnj11
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medicine
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mexican-american
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pro12ala
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7-like
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igf2bp2
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haplogenotype
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cdkal1
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drug development
- 3.4.22.B30
- calpains
- mellitus
-
ucsnp-43
-
polycystic
-
tcf7l2
-
mexican
-
kcnj11
- medicine
-
mexican-american
-
pro12ala
-
7-like
-
igf2bp2
-
haplogenotype
- cdkal1
- drug development
Reaction
broad endopeptidase specificity =
Synonyms
calpain 10, calpain-10, CAPN10
ECTree
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Inhibitors
Inhibitors on EC 3.4.22.B30 - calpain 10
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CYGAK disulfide
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valuable tool to prevent Ca2+ induced mitochondrial dysfunction and explore the function of calpain 10
N-[(2R)-4-hydroxy-1-oxobutan-2-yl]-N2-(phenylcarbamothioyl)-L-leucinamide
binding structure, the inhibitor shows interactions with the Cys115, Gly207, Gly20,8 and Gly271 residues, overview. Reversible intramolecular conversion of the cyclic hemiacetal form of SNJ-1715 to the free aldehyde form
N-[(3R)-2-hydroxytetrahydrofuran-3-yl]-N2-(phenylcarbamothioyl)-L-leucinamide
binding structure, the inhibitor shows interactions with the Cys115, Gly207, Gly20,8 and Gly271 residues, overview. Reversible intramolecular conversion of the cyclic hemiacetal form of SNJ-1715 to the free aldehyde form
pan-calpain inhibitors reduce AngII-induced aldosterone production in 2 adrenal glomerulosa cell models, primary bovine zona glomerulosa and human adrenocortical carcinoma cells
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additional information
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pan-calpain inhibitors reduce AngII-induced aldosterone production in 2 adrenal glomerulosa cell models, primary bovine zona glomerulosa and human adrenocortical carcinoma cells
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