Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.22.B30: calpain 10

This is an abbreviated version!
For detailed information about calpain 10, go to the full flat file.

Word Map on EC 3.4.22.B30

Reaction

broad endopeptidase specificity =

Synonyms

calpain 10, calpain-10, CAPN10

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B30 calpain 10

Inhibitors

Inhibitors on EC 3.4.22.B30 - calpain 10

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
calpastatin
-
-
calpeptin
CYGAK
-
inhibitory activity of CYGAK to calpain 10 is independent of Ca2+
CYGAK disulfide
-
valuable tool to prevent Ca2+ induced mitochondrial dysfunction and explore the function of calpain 10
N-[(2R)-4-hydroxy-1-oxobutan-2-yl]-N2-(phenylcarbamothioyl)-L-leucinamide
binding structure, the inhibitor shows interactions with the Cys115, Gly207, Gly20,8 and Gly271 residues, overview. Reversible intramolecular conversion of the cyclic hemiacetal form of SNJ-1715 to the free aldehyde form
N-[(3R)-2-hydroxytetrahydrofuran-3-yl]-N2-(phenylcarbamothioyl)-L-leucinamide
binding structure, the inhibitor shows interactions with the Cys115, Gly207, Gly20,8 and Gly271 residues, overview. Reversible intramolecular conversion of the cyclic hemiacetal form of SNJ-1715 to the free aldehyde form
additional information
-