3.4.22.B30: calpain 10

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For detailed information about calpain 10, go to the full flat file.

Word Map on EC 3.4.22.B30

3.4.22.B30

calpains

mellitus

ucsnp-43

polycystic

tcf7l2

mexican

kcnj11

medicine

mexican-american

pro12ala

7-like

igf2bp2

haplogenotype

cdkal1

drug development

Reaction

broad endopeptidase specificity =

Synonyms

calpain 10, calpain-10, CAPN10

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.B30 calpain 10

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Results	in table
6	Activating Compound
4	AA Sequence
15	Application
1	CAS Registry Number
7	Cloned(Commentary)
991	Disease/ Diagnostics
5	Expression
16	General Information
3	IC50 Value
17	Inhibitors
23	Localization
11	Metals/Ions
10	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
55	Organism
7	Protein Variants
2	Purification (Commentary)
1	Reaction
2	Reaction Type
54	Reference
58	Source Tissue
37	Substrates and Products (Substrate)
8	Subunits
35	Synonyms

Source Tissue

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Source Tissue on EC 3.4.22.B30 - calpain 10

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adrenal glomerulosa cell

in Capn10-/- mouse embryonic fibroblasts, MAP1B is localized at actin filaments rather than at microtubules

two major isoforms with intact N-terminus but different C-terminal T domains

it is proposed that a defective CAPN10 pre-mRNA processing is responsible for the decreased levels of SNP-43 A-allele transcripts in peripheral white cells of healthy and T2D individuals

renal proximal tubule