3.4.22.47: gingipain K

This is an abbreviated version!
For detailed information about gingipain K, go to the full flat file.

Word Map on EC 3.4.22.47

3.4.22.47

gingivalis

porphyromonas

periodontal

gingipains

arg-gingipains

proteinases

arginine-specific

crevicular

keystone

hrgpa

subgingival

molecular biology

black-pigmented

gingivalis-induced

coaggregation

medicine

arg-specific

gingipain-deficient

Reaction

endopeptidase with strict specificity for lysyl bonds =

Synonyms

gingipain, gingipain K, HbR, K-gingipain, K-specific gingipain protease, KGP, Lys-gingipain, Lys-specific cysteine proteinase gingipain, lysine gingipain, lysine-sepcific cysteine protease, lysine-specific gingipain, lysine-specific gingipain K, lysine-specific gingipain protease, lysine-specific gingipain proteinase, lysine-specific proteinase, porphypain, PrtP proteinase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.47 gingipain K

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Results	in table
15	Activating Compound
59	AA Sequence
7	Application
1	CAS Registry Number
5	Cloned(Commentary)
3	Crystallization (Commentary)
14	General Information
1	General Stability
53	Inhibitors
3	Ki Value [mM]
7	KM Value [mM]
14	Localization
1	Metals/Ions
10	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
126	Organism
7	PDB ID
21	pH Optimum
1	pH Range
3	pH Stability
4	Posttranslational Modification
18	Protein Variants
11	Purification (Commentary)
3	Reaction
1	Reaction Type
65	Reference
6	Source Tissue
3	Specific Activity [micromol/min/mg]
105	Substrates and Products (Substrate)
15	Subunits
93	Synonyms
19	Temperature Optimum [°C]
6	Temperature Stability [°C]
1	Turnover Number [1/s]

KM Value

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KM Value on EC 3.4.22.47 - gingipain K

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0.18

benzyloxycarbonyl-L-Lys-p-nitroanilide

Porphyromonas gingivalis

pH 8.5, 37°C

638843

0.2

D-Val-Leu-Lys-p-nitroanilide

Porphyromonas gingivalis

pH 8.5, 37°C

638843

0.126

D-Val-Phe-Lys-p-nitroanilide

Porphyromonas gingivalis

pH 8.5, 37°C

638843

0.0029

hemoglobin

Porphyromonas gingivalis

pH 7.6, 37°C, human serum hemoglobin

638851

0.05

N-p-tosyl-Gly-Pro-Lys-p-nitroanilide

Porphyromonas gingivalis

pH 8.5, 37°C

638843

additional information

2 entries