3.4.21.B59: granzyme H

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For detailed information about granzyme H, go to the full flat file.

Word Map on EC 3.4.21.B59

3.4.21.B59

killer

perforin

ctl

chymotrypsin-like

chymase

diagnostics

Reaction

cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites =

Synonyms

Granzyme H, GrH

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.B59 granzyme H

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Results	in table
1	AA Sequence
1	Application
1	Cloned(Commentary)
18	Disease/ Diagnostics
2	General Information
2	Localization
1	Metals/Ions
1	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
1	Posttranslational Modification
1	Protein Variants
1	Purification (Commentary)
2	Reaction
2	Reference
6	Source Tissue
3	Substrates and Products (Substrate)
2	Synonyms
1	Temperature Optimum [°C]

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Reference on EC 3.4.21.B59 - granzyme H

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732517

Ewen, C.L.; Kane, K.P.; Bleackley, R.C.

Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation

Mol. Immunol.

309-318

2013

Homo sapiens (P20718), Homo sapiens

23352961

753108

Dencker, M.; Bj�rgell, O.; Hlebowicz, J.

Effect of food intake on 92 oncological biomarkers by the Proseek Oncology II panel

BMC Res. Notes

199

2019

Homo sapiens (P20718)

30940215