3.4.21.B59: granzyme H

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For detailed information about granzyme H, go to the full flat file.

Reaction

cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites =

Synonyms

Granzyme H, GrH

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.B59 granzyme H

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1	AA Sequence
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1	Cloned(Commentary)
18	Disease/ Diagnostics
2	General Information
2	Localization
1	Metals/Ions
1	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
1	Posttranslational Modification
1	Protein Variants
1	Purification (Commentary)
2	Reaction
2	Reference
6	Source Tissue
3	Substrates and Products (Substrate)
2	Synonyms
1	Temperature Optimum [°C]

Reaction

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Reaction on EC 3.4.21.B59 - granzyme H

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites

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preferential cleavage: -Asp-/- >> -Asn-/- > -Met-/-, -Ser-/-

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