3.4.21.112: site-1 protease

This is an abbreviated version!
For detailed information about site-1 protease, go to the full flat file.

Word Map on EC 3.4.21.112

3.4.21.112

srebps

proprotein

furin

site-2

atf6

subtilase

lassa

arenaviruses

medicine

cleavage-activating

mbtps1

nonbasic

crimean-congo

mucolipidosis

glcnac-1-phosphotransferase

n-acetylglucosamine-1-phosphotransferase

degradation

Reaction

processes precursors containing basic and hydrophobic/aliphatic residues at P4 and P2, respectively, with a relatively relaxed acceptance of amino acids at P1 and P3 =

Synonyms

convertase site 1 protease, dS1P, hSKI-1, kexin, membrane-bound transcription factor protease, site-1, MEROPS S08.8063, PCSK8, prohormone convertase subtilisin-kexin isoenzyme-1, protease responsible for activating sigmaW, PrsW, S08.063, S1P, site 1 protease, site-1 protease, SK-1, SKI-1, SKI-1/S1P, SREBP site 1 protease, subtilisin kexin isoenzyme-1, subtilisin kexin isozyme 1/site 1 protease, subtilisin kexin isozyme-1, subtilisin kexin isozyme-1(SK-1)/site 1 protease (S1P), subtilisin kexin isozyme-1/site-1 protease, subtilisin kexin-isozyme-1, subtilisin-kexin isoenzyme-1, subtilisin-kexin-isozyme, subtilisin/kexin isozyme 1, YPDC

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.112 site-1 protease

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
4	Activating Compound
37	AA Sequence
15	Application
1	CAS Registry Number
19	Cloned(Commentary)
126	Disease/ Diagnostics
17	General Information
26	IC50 Value
70	Inhibitors
11	Ki Value [mM]
37	KM Value [mM]
26	Localization
8	Metals/Ions
9	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
61	Organism
4	pH Optimum
11	Posttranslational Modification
39	Protein Variants
4	Purification (Commentary)
1	Reaction
18	Reaction Type
53	Reference
55	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
82	Substrates and Products (Substrate)
1	Subunits
81	Synonyms
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

Localization

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Localization on EC 3.4.21.112 - site-1 protease

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Localization Search

endoplasmic reticulum

139

additional information

Homo sapiens

Q14703

the truncated mutant DELTA AC SKI-1/S1P BTMD, truncated before the transmembrane domain, stays in the endoplasmic reticulum

732162