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Literature summary for 3.4.21.112 extracted from

  • Lenz, O.; Ter Meulen, J.; Klenk, H.D.; Seidah, N.G.; Garten, W.
    The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P (2001), Proc. Natl. Acad. Sci. USA, 98, 12701-12702.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.112

Application

Application Comment Organism
additional information cleaves glycoprotein, the only cleaved glycoprotein is incorporated into virions and this is necessary for the formation of infectious virus Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
pCDNA3.1-SKI/S1P expressed in CHO-K1, BHK, Vero, or SRD-12B cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Lassa virus glycoprotein precursor GP-C + H2O cleavage at the C-terminal end of the recognition motif R-R-L-L Homo sapiens Lassa virus glycoprotein GP-2 + ?
-
 ?

Synonyms

Synonyms Comment Organism
SKI-1/S1P
-
 Homo sapiens