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Literature summary for 3.4.21.112 extracted from

  • Ye, J.; Rawson, R.B.; Komuro, R.; Chen, X.; Dave, U.P.; Prywes, R.; Brown, M.S.; Goldstein, J.L.
    ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs (2000), Mol. Cell, 6, 1355-1364.
    View publication on PubMed
Search for more literature for 3.4.21.112

Application

Application Comment Organism
additional information S1P is required for the endoplasmic reticulum stress response as well as for lipid synthesis Cricetulus griseus

Cloned(Commentary)

Cloned (Comment) Organism
into pcMV-S1P-Myc Cricetulus griseus

Protein Variants

Protein Variants Comment Organism
additional information S1P-deficient cells, ATF6 processing partially blocked Cricetulus griseus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Cricetulus griseus 5783
-

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATF6 + H2O i.e. activating transcription factor 6 Cricetulus griseus ?
-
 ?

Synonyms

Synonyms Comment Organism
S1P
-
 Cricetulus griseus