3.4.21.109: matriptase

This is an abbreviated version!
For detailed information about matriptase, go to the full flat file.

Reaction

cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position =

Synonyms

Epi/MTP, epithin, epithin/matriptase, influenza virus-activating protease, matriptase, matriptase-1, matriptase-2, matriptase-3, matriptase1, matriptase1a, membrane-type serine protease 1, membrane-type serine protease 1/matripase, membrane-type serine protease-1, membrane-type serine protease1, membrane-type serine proteinase matripase, membrane-type serine proteinase matriptase, More, MT-2, MT-SP-1, MT-SP1, MT-SP1/matripase, MT2, notopleural, prostamin, PRSS14, r-matripase, serine protease matriptase-2, serine protease SNC19/matripase, SNC19, ST-14, ST14, suppression of tumorigenecity 14, suppressor of tumorigenicity 14, suppressor of tumorigenicity 14 protein, suppressor of tumorigenicity-14, TADG-15, TADG15, TMPRSS6, transmembrane serine protease 6, tumor-associated differentially expressed gene-15, tumor-associated type II transmembrane serine protease, type 2 transmembrane serine protease, type II transmembrane protease, type II transmembrane serine protease

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.109 matriptase

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Results	in table
32	Activating Compound
340	AA Sequence
23	Application
1	CAS Registry Number
48	Cloned(Commentary)
5	Crystallization (Commentary)
2424	Disease/ Diagnostics
11	Expression
55	General Information
2	General Stability
2	IC50 Value
292	Inhibitors
11	kcat/KM [mM/s]
232	Ki Value [mM]
61	KM Value [mM]
104	Localization
4	Metals/Ions
79	Molecular Weight [Da]
157	Natural Substrates/ Products (Substrates)
125	Organism
23	PDB ID
19	pH Optimum
1	pH Range
42	Posttranslational Modification
95	Protein Variants
23	Purification (Commentary)
9	Reaction
37	Reaction Type
122	Reference
3	Renatured (Commentary)
430	Source Tissue
3	Specific Activity [micromol/min/mg]
322	Substrates and Products (Substrate)
26	Subunits
193	Synonyms
13	Temperature Optimum [°C]
40	Turnover Number [1/s]