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3.2.1.139: alpha-glucuronidase

This is an abbreviated version!
For detailed information about alpha-glucuronidase, go to the full flat file.

Word Map on EC 3.2.1.139

Reaction

an alpha-D-glucuronoside
+
H2O
=
an alcohol
+
D-glucuronate

Synonyms

(4-O-methyl)-alpha-glucuronidase, 4-O-methylglucuronidase, aGlu, Agu115, Agu115A, Agu4B, AguA, alpha-(4-O-methyl)-D-glucuronidase, alpha-D-glucuronidase, Alpha-glucosiduronase, alpha-glucosiduronate glucuronohydrolase, alpha-glucuronidase, amylouronate hydrolase-I, Aryl alpha-glucuronidase, AugA, AUH-I, BoAgu115A, DEG75-AG, GH115, GH115 glucuronidase, GH67, GH67 alpha-glucuronidase, GlcA115A, GlcA67A, GLRI, glucuronidase, alpha-, glycosyl hydrolase family 115 alpha-glucuronidase, non-xylanolytic alpha-glucuronidase, p-nitrophenyl alpha-D-glucuronide-hydrolyzing enzyme, Pjdr2_5977, PNP-GAase, RUM630-AG, Sde_1755, TrDCase, TreDCase

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.139 alpha-glucuronidase

Temperature Stability

Temperature Stability on EC 3.2.1.139 - alpha-glucuronidase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10 - 40
-
AUH-I is stable at 10-40°C, but starts to lose the activity above 40°C
30
-
pH 4.0, 24 h, stable below
35
half-life 90 min
45
-
4 h, 20% loss of activity
55
rapid inactivation above
55 - 75
-
partial inactivation, but thereafter the residual activity remains nearly constant for several days
73
-
melting temperature of mutant enzyme W328E/R329T/R665N is 72.9°C, melting temperature of wild-type enzyme is 73.4°C
73.4
-
denaturation at
80
30 min, 10% loss of activity
90
30 min, complete inactivation
additional information