220.127.116.11: GDP-mannose 6-dehydrogenase
This is an abbreviated version, for detailed information about GDP-mannose 6-dehydrogenase, go to the full flat file.
algD, GDP mannose dehydrogenase, GDP-mannose dehydrogenase, GMD, GMD1, GMD2, guanosine diphospho-D-mannose dehydrogenase, guanosine diphosphomannose dehydrogenase
Engineering on EC 18.104.22.168 - GDP-mannose 6-dehydrogenase
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site-directed mutagenesis, 1.8fold increased Vmax compared to the wild-type enzyme
site-directed mutagenesis, 250fold reduced Vmax, 5fold increased KM, and reduced sensitivity to penicillic acid inactivation compared to the wild-type enzyme