1.1.1.132: GDP-mannose 6-dehydrogenase

This is an abbreviated version, for detailed information about GDP-mannose 6-dehydrogenase, go to the full flat file.

Reaction

GDP-D-mannose
+ 2 NAD+ +
H2O
=
GDP-D-mannuronate
+ 2 NADH + 2 H+

Synonyms

algD, GDP mannose dehydrogenase, GDP-mannose dehydrogenase, GMD, guanosine diphospho-D-mannose dehydrogenase, guanosine diphosphomannose dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.132 GDP-mannose 6-dehydrogenase

Metals Ions

Metals Ions on EC 1.1.1.132 - GDP-mannose 6-dehydrogenase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CoCl2
-
at 1 mM CoCl2 44% enzymatic activity
CuSO4
-
at 1 mM CuSO4 no enzymatic activity
FeCl3
-
at 1 mM FeCl3 49% enzymatic activity
FeSO4
-
at 1 mM FeSO4 77% enzymatic activity
K+
-
increases activity
Na+
-
increases activity
PCMB
-
0.025 mM, 0.8% activity