EC Number   |
Protein Variants |
Reference |
|---|
   7.6.2.1 | A270T |
mutant and wild-type enzymes have similar activities at 30°C, but the mutant activity is decreased significant at 42°C |
656078 |
| 7.6.2.1 | D256E |
the mutant shows reduced activity with phosphatidylcholine, increased activity with phosphatidylserine, and increased activity with sphingomyelin compared to the wild type enzyme |
749181 |
| 7.6.2.1 | E123A |
the mutant shows about 80% of wild type activity |
747769 |
| 7.6.2.1 | E126A |
the mutant shows about 10% of wild type activity. The mutation leads to reduced glycosylation of the accessory subunit CDC50A |
747769 |
| 7.6.2.1 | E181Q |
the mutant shows strongly reduced activity compared to the wild type enzyme |
749361 |
| 7.6.2.1 | E186Q |
inactive |
749361 |
| 7.6.2.1 | E198Q |
inactive |
747769 |
| 7.6.2.1 | E203Q |
the mutant lacks ATPase activity |
747650 |
| 7.6.2.1 | E371Q |
affinity to phosphatidylserine similar to wild-type |
735189 |
| 7.6.2.1 | F213S |
the mutant shows increased activity with phosphatidylcholine, phosphatidylserine, and sphingomyelin compared to the wild type enzyme |
749181 |
