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Information on EC 7.6.2.1 - P-type phospholipid transporter

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IUBMB Comments
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Different forms of the enzyme move phospholipids such as phosphatidylcholine, lyso-phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, phosphatidyglycerol, sphingomyelin and glucosylceramide from one membrane face to the other ('flippase').
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The expected taxonomic range for this enzyme is: Eukaryota, Archaea, Bacteria
Synonyms
ABCB1, ABCB4, ALA1, ALA10, ALA11, ALA12, ALA2, ALA3, ALA4, ALA5, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + phospholipid [side 1] = ADP + phosphate + phospholipid [side 2]
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