EC Number   |
Protein Variants |
Reference |
|---|
   3.6.4.6 | E233Q |
a mutant protein with very low ATPase activity. In the presence of ADP recombinant mutant enzyme forms dimers. In contrast, the addition of ATP results in the formation of a large complex with at least ten subunits |
724447 |
| 3.6.4.6 | K266A |
ATP-binding mutant |
686724 |
| 3.6.4.6 | E232Q |
ATPase-deficient mutant |
689461 |
| 3.6.4.6 | more |
construction of a Vps4p deletion mutant |
-, 735147 |
| 3.6.4.6 | more |
construction of Vps4 knockout mutants, loss of Vps4 affects multiple signaling pathways, phenotypes, detailed overview |
733702 |
| 3.6.4.6 | K549A |
decrease in NSF vesicular transport activity |
656661 |
| 3.6.4.6 | G89D |
higher intrinsic ATPase activity than wild-type, no stimulation by Sec17 |
654648 |
| 3.6.4.6 | E329Q |
hydrolysis mutant |
686724 |
| 3.6.4.6 | E350Q |
hydrolysis mutant |
686724 |
| 3.6.4.6 | E329Q |
in contrast to wild-type NFS E329Q mutant is enriched on various structures throughout the cell and is only minimally released by saponin permeabilization |
656763 |
