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Results 1 - 4 of 4
EC Number Protein Variants Commentary Reference
Display the reaction diagram Show all sequences 3.4.21.122more TMPRSS2 mutants lacking exon 4 or exon 5 are devoid of enzymatic activity 754531
Display the reaction diagram Show all sequences 3.4.21.122R255Q mutation results in a loss of autoproteolytic cleavage. The mutant enzyme appeared as a single protein species with an apparent molecular weight of 70000, the cleaved 32000 MW protease domain is not detected 764399
Display the reaction diagram Show all sequences 3.4.21.122S441A inactive 753762, 754533
Display the reaction diagram Show all sequences 3.4.21.122S441A mutation results in a loss of autoproteolytic cleavage. The mutant enzyme appeared as a single protein species with an apparent molecular weight of 70000, the cleaved 32000 MW protease domain is not detected 764399
Results 1 - 4 of 4