EC Number   |
Protein Variants |
Reference |
|---|
    3.3.2.10 | C154Y |
a naturally occuring polymorphism, the substitutions results in an enzyme with increased epoxide hydrolase activity, the mutation is associated with with ischemic stroke risk |
708573 |
| 3.3.2.10 | C154Y |
single nucleotide polymorphisms of gene EPHX2, the mutation leads to slightly reduced cell death |
707067 |
| 3.3.2.10 | C154Y |
site-directed mutagenesis, the mutant shows a hydrolase/phosphatase ratio of 2.2, compared to the wild-type ratio of 1.0 |
660799 |
| 3.3.2.10 | C154Y |
the mutant has a significantly higher phosphatase activity than wild type |
732298 |
| 3.3.2.10 | C780T |
naturally occuring mutation involved in renal cortex of Wistar-Kyoto rats |
708238 |
| 3.3.2.10 | D11A |
inactive |
699556 |
| 3.3.2.10 | D11N |
mutant with strongly reduced phosphatase activity of sEH (2fold decrease in Km and 9fold decrease in kcat compared to the wild type enzyme), the N-terminal domain has phosphatase activity, the C-terminal domain has epoxide hydrolase activity |
699556 |
| 3.3.2.10 | D184A |
the mutation results in a complete loss of the phosphatase activity of sEH, the N-terminal domain has phosphatase activity, the C-terminal domain has epoxide hydrolase activity |
699556 |
| 3.3.2.10 | D184N |
the mutation results in a complete loss of the phosphatase activity of sEH, the N-terminal domain has phosphatase activity, the C-terminal domain has epoxide hydrolase activity |
699556 |
| 3.3.2.10 | D185A |
the mutation leads to a completely inactive sEH phosphatase, the N-terminal domain has phosphatase activity, the C-terminal domain has epoxide hydrolase activity |
699556 |
