EC Number   |
Protein Variants |
Reference |
|---|
    2.3.1.179 | more |
construction of a KAS2 T-DNA insertion mutant, the mutation causes arrest of embryonal development and embryo lethality, phenotype, overview |
703859 |
| 2.3.1.179 | more |
construction of KASII knockout mutants by T-DNA disruption, knockout alleles fab1-1 and fab1-2, strong seed-specific hairpin-RNAi reductions in FAB1 expression resulted in abortion of about 1/4 of the embryos in an apparent phenocopy of fab1-2 homozygosity, in less severe FAB1 hairpin-RNAi individuals, embryos developed normally and exhibited a 1:2:1 segregation ratio for palmitate accumulation, thus, early embryo development appears sensitive to elevated 16:0, whereas at later stages, up to 53% of 16:0, i.e. a 7-fold increase over wild-type levels, is tolerated, Fab1-1 mutant plants show about 60% of wild-type enzyme activity and about 17% palm-like oil accumulation compared to the wild-type plants, phenotypes, overview |
676894 |
| 2.3.1.179 | E383A |
crystal structure determination and comparison to the wild-type enzyme, the mutation E383A appears to play a key role in disfavouring the less desirable triclinic crystal form and in generating a new surface for a packing interaction that stabilizes the new crystal form |
701462 |
| 2.3.1.179 | more |
enzyme overexpression in a strain deficient in palmitoyl-acyl carrier protein [ACP] thioesterase, EC 3.1.2.14, for improvement of palm oil production in Elaeis guineensis |
736673 |
| 2.3.1.179 | more |
expression of Clostridium acetobutylicium FabF1 restores thermal control of fatty acid composition to an Escherichia coli FabF null mutant strain. FabF1 expression leads a modest conversion of cis-3-decenoyl-[acyl-carrier-protein] to trans-2-cis-5-dodecadienoyl-[acyl carrier-protein]. An Escherichia coli fabF- strain in which Clostridium acetobutylicium FabF1 is expressed from the lac promoter of a low copy number vector closely mimicks the changes in fatty acid composition seen in wild type Escherichia coli strains upon changes in growth temperature. Expression of Clostridium acetobutylicium FabF1 restores cis-vaccenate synthesis at all temperatures, but is much more effective at 30°C than at 37°C or 42°C |
702905 |
| 2.3.1.179 | more |
in vitro complementation of the enzyme-deficient Escherichia coli CY244 strain, shows that Plasmodium falciparum FabB/F functions like Escherichia coli FabF as the growth of the mutant cells can be rescued only in the presence of oleic acid |
704117 |
| 2.3.1.179 | F107I |
less efficient than wild type protein |
719275 |
| 2.3.1.179 | F107L |
less efficient than wild type protein |
719275 |
| 2.3.1.179 | R206G |
R206 impairs the binding of CoA |
718888 |
| 2.3.1.179 | C164Q |
site-directed mutagenesis, a mutant in which the binding site is altered to resemble the substrate-bound state |
735397 |
