EC Number |
Protein Variants |
Reference |
---|
1.3.7.4 | D116N |
mutant still retains the ability of substrate binding, but with only 1.5% relative activity of wild type protein |
687760 |
1.3.7.4 | D146N |
mutant completely loses catalytic activity and also the ability of biliverdin binding |
687760 |
1.3.7.4 | D256E |
mutant retains only partial activity |
687760 |
1.3.7.4 | N133 |
mutant produces only partial activity |
687760 |
1.3.7.4 | R252Q |
mutant loses catalytic activity and the ability of substrate binding |
687760 |
1.3.7.4 | E110Q |
site-directed mutagenesis, the mutant shows 321.7% of wild-type activity |
712484 |
1.3.7.4 | E187Q |
site-directed mutagenesis, the mutant shows 20.3% of wild-type activity |
712484 |
1.3.7.4 | H259Q |
site-directed mutagenesis, the mutant shows 123.4% of wild-type activity |
712484 |
1.3.7.4 | K183Q |
site-directed mutagenesis, the mutant shows 24.6% of wild-type activity |
712484 |
1.3.7.4 | K255Q |
site-directed mutagenesis, the mutant shows 11.7% of wild-type activity |
712484 |