EC Number   |
Protein Variants |
Reference |
|---|
   3.1.3.67 | C124S |
PTEN mutant is devoid of phosphatase activity and fails to modulate p75NTR expression, indicating that phosphatase activity is required for PTEN regulation of neurotophin receptor p75NTR |
690780 |
| 3.1.3.67 | C124S |
the PTEN mutant lacks phosphatase activity, but is not altered in TRPC6 activity |
715544 |
| 3.1.3.67 | C136Y |
inactive mutant enzyme |
650767 |
| 3.1.3.67 | C645S |
inactive mutant |
732810 |
| 3.1.3.67 | C71Y |
inactive mutant enzyme |
650767 |
| 3.1.3.67 | D107Y |
inactive mutant enzyme |
650767 |
| 3.1.3.67 | D331G |
mutant enzyme with partial activity |
650767 |
| 3.1.3.67 | D92A |
catalytically inert mutant enzyme, retains partial ability to induce cells to accumulate in G1 |
653626 |
| 3.1.3.67 | DELTA1-15 |
phosphatidylinositol 4,5-biphosphate has no effect on binding of PTEN16-403 |
690927 |
| 3.1.3.67 | DELTA352-403 |
truncated enzyme binds strongly to the plasma membrane, an effect that is reversed by co-expression of the remainder of the molecule, PTEN 352-403 |
694916 |
