EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.11.3 | Arthritis |
1224809 |
Desoxyribonuclease activity in the serum and spleen of rats with mycoplasma induced arthritis. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
1
0 |
| 3.1.11.3 | Arthritis, Experimental |
1224809 |
Desoxyribonuclease activity in the serum and spleen of rats with mycoplasma induced arthritis. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
1
0 |
| 3.1.11.3 | Arthritis, Rheumatoid |
20496420 |
Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
4
3
0 |
| 3.1.11.3 | Ataxia Telangiectasia |
6320855 |
The use of recombinant DNA plasmids for the determination of DNA-repair and recombination in cultured mammalian cells. |
unassigned |
0 |
| 3.1.11.3 | Atherosclerosis |
24552169 |
IL-24 Gene Polymorphisms Are Associated with Cardiometabolic Parameters and Cardiovascular Risk Factors But Not with Premature Coronary Artery Disease: The Genetics of Atherosclerotic Disease Mexican Study. |
causal interaction
ongoing research
unassigned |
2
1
0 |
| 3.1.11.3 | Autoimmune Diseases |
18045533 |
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease. |
causal interaction
unassigned |
3
0 |
| 3.1.11.3 | Autoimmune Diseases |
22071149 |
Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease. |
causal interaction
unassigned |
4
0 |
| 3.1.11.3 | Autoimmune Diseases |
25848017 |
Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease. |
unassigned |
0 |
| 3.1.11.3 | Autoimmune Diseases |
28334850 |
Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion. |
causal interaction
unassigned |
1
0 |
| 3.1.11.3 | Autoimmune Diseases |
30955997 |
An emerging role for calcium signalling in innate and autoimmunity via the cGAS-STING axis. |
causal interaction
unassigned |
2
0 |
