EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.2.4.2 | Acidosis, Lactic |
6897145 |
Congenital lactic acidosis, alpha-ketoglutaric aciduria and variant form of maple syrup urine disease due to a single enzyme defect: dihydrolipoyl dehydrogenase deficiency. |
causal interaction
unassigned |
4
0 |
| 1.2.4.2 | Acidosis, Lactic |
8815392 |
Alterations of thiamine phosphorylation and of thiamine-dependent enzymes in Alzheimer's disease. |
causal interaction
unassigned |
4
0 |
| 1.2.4.2 | Acidosis, Lactic |
24256811 |
Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes. |
causal interaction
unassigned |
4
0 |
| 1.2.4.2 | Adenocarcinoma |
30967137 |
The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
3
2
0 |
| 1.2.4.2 | Adenocarcinoma of Lung |
32466567 |
Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action. |
causal interaction
unassigned |
1
0 |
| 1.2.4.2 | Alzheimer Disease |
2087217 |
Thiamine-dependent enzyme changes in temporal cortex of patients with Alzheimer's disease. |
diagnostic usage
ongoing research
unassigned |
1
2
0 |
| 1.2.4.2 | Alzheimer Disease |
7974008 |
Pseudogene of dihydrolipoyl succinyltransferase (E2k) found by PCR amplification and direct sequencing of rodent-human cell hybrid DNAs. |
causal interaction
unassigned |
2
0 |
| 1.2.4.2 | Alzheimer Disease |
8122883 |
Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 1.2.4.2 | Alzheimer Disease |
8245957 |
Brain alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. |
causal interaction
diagnostic usage
ongoing research
unassigned |
3
3
1
0 |
| 1.2.4.2 | Alzheimer Disease |
8619544 |
Brain protein and alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
2
2
0 |
