EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.2.4.2 | Thiamine Deficiency |
19067139 |
Thiamine deficiency-related brain dysfunction in chronic liver failure. |
unassigned |
0 |
| 1.2.4.2 | Thiamine Deficiency |
21517848 |
Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels. |
unassigned |
0 |
| 1.2.4.2 | Thyroid Cancer, Papillary |
33405394 |
OGDHL closely associates with tumor microenvironment and can serve as a prognostic biomarker for papillary thyroid cancer. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
1
2
2
0 |
| 1.2.4.2 | Tuberculosis |
16045627 |
Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. |
unassigned |
0 |
| 1.2.4.2 | Tuberculosis |
16522631 |
Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein. |
unassigned |
0 |
| 1.2.4.2 | Tuberculosis |
19936047 |
An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. |
therapeutic application
unassigned |
1
0 |
| 1.2.4.2 | Tuberculosis |
21867916 |
Functional Plasticity and Allosteric Regulation of ?-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism. |
unassigned |
0 |
| 1.2.4.2 | Tuberculosis |
25750047 |
The glyoxylate shunt is essential for CO2-requiring oligotrophic growth of Rhodococcus erythropolis N9T-4. |
diagnostic usage
unassigned |
1
0 |
| 1.2.4.2 | Uterine Cervical Neoplasms |
23152800 |
OGDHL is a modifier of AKT-dependent signaling and NF-?B function. |
causal interaction
unassigned |
3
0 |
| 1.2.4.2 | Wernicke Encephalopathy |
3724963 |
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy. 2. alpha-Ketoglutarate dehydrogenase. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
