EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.14.14.17 | Carcinoma, Hepatocellular |
25787749 |
Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells. |
causal interaction
diagnostic usage
unassigned |
1
3
0 |
| 1.14.14.17 | Carcinoma, Hepatocellular |
29669855 |
Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
1
2
0 |
| 1.14.14.17 | Carcinoma, Hepatocellular |
32216563 |
High Squalene Epoxidase in Tumors Predicts Worse Survival in Patients With Hepatocellular Carcinoma: Integrated Bioinformatic Analysis on NAFLD and HCC. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
4
1
0 |
| 1.14.14.17 | Carcinoma, Squamous Cell |
30734525 |
Squalene epoxidase promotes the proliferation and metastasis of lung squamous cell carcinoma cells though extracellular signal-regulated kinase signaling. |
causal interaction
ongoing research
unassigned |
4
4
0 |
| 1.14.14.17 | Carcinoma, Squamous Cell |
34163246 |
High SQLE Expression and Gene Amplification Correlates with Poor Prognosis in Head and Neck Squamous Cell Carcinoma. |
diagnostic usage
ongoing research
unassigned |
4
1
0 |
| 1.14.14.17 | Chagas Disease |
17981471 |
Heteroallyl-containing 5-nitrofuranes as new anti-Trypanosoma cruzi agents with a dual mechanism of action. |
therapeutic application
unassigned |
4
0 |
| 1.14.14.17 | Cholelithiasis |
14684588 |
Cholesterol synthesis inhibition distal to squalene upregulates biliary phospholipid secretion and counteracts cholelithiasis in the genetically prone C57L/J mouse. |
ongoing research
therapeutic application
unassigned |
3
3
0 |
| 1.14.14.17 | Colorectal Neoplasms |
27358048 |
Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia. |
ongoing research
therapeutic application
unassigned |
2
1
0 |
| 1.14.14.17 | Colorectal Neoplasms |
31072053 |
Squalene Epoxidase Correlates E-Cadherin Expression and Overall Survival in Colorectal Cancer Patients: The Impact on Prognosis and Correlation to Clinicopathologic Features |
diagnostic usage
unassigned |
4
0 |
| 1.14.14.17 | Colorectal Neoplasms |
32946903 |
Reduction of squalene epoxidase by cholesterol accumulation accelerates colorectal cancer progression and metastasis. |
unassigned |
0 |
