EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.4.23.5 | 0.0000086 |
- |
N2-[N-[(2-bromo-4,5-dimethoxyphenyl)acetyl]carbamimidoyl]-3-cyclohexyl-N-(4-fluoro-3-methoxybenzyl)-D-alaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.00001 |
- |
pepstatin A |
IC50 less than 0.00001 mM, pH and temperature not specified in the publication |
712050 |
| 3.4.23.5 | 0.000015 |
- |
N1-[(2S,3S)-3-hydroxy-5-([(2S)-4-methyl-1-[(2-methylpropyl)amino]-1-oxopentan-2-yl]amino)-5-oxo-1-phenylpentan-2-yl]-5-[(methanesulfonyl)(methyl)amino]-N3-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide |
pH and temperature not specified in the publication |
754469 |
| 3.4.23.5 | 0.000024 |
- |
N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-N-(4-fluoro-3-methoxybenzyl)-D-leucinamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000027 |
- |
(5S,8S,11S,12S,16S,19S,22R)-8-(3-amino-3-oxopropyl)-11,22-dibenzyl-12-hydroxy-7,19,21-trimethyl-16-(2-methylpropyl)-3,6,9,14,17,20-hexaoxo-1-phenyl-5-(propan-2-yl)-2-oxa-4,7,10,15,18,21-hexaazatricosan-23-oic acid |
at pH 3.5 and 25°C |
754470 |
| 3.4.23.5 | 0.000044 |
- |
3-cyclohexyl-N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-N-[4-(1H-tetrazol-5-yl)benzyl]-D-alaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000058 |
- |
N-(3,4-dimethoxybenzyl)-Na-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-D-phenylalaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000067 |
- |
N-(3,4-dimethoxybenzyl)-N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-D-leucinamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000081 |
- |
3-cyclohexyl-N2-[N-[(3,4-dimethoxyphenyl)acetyl]carbamimidoyl]-N-[3-fluoro-4-(1H-tetrazol-5-yl)benzyl]-D-alaninamide |
at pH 5.5 and 37°C |
731454 |
| 3.4.23.5 | 0.000085 |
- |
2-bromo-N-[(2S,3S)-4-[[2-(2,4-dichlorophenyl)ethyl][3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoyl]amino]-3-hydroxy-1-(3-phenoxyphenyl)butan-2-yl]-4,5-dimethoxybenzamide |
at pH 5.5 and 37°C |
731454 |
