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EC Number	Cofactor	Commentary	Reference
2.7.11.22	cyclin	regulatory subunit of CDK	664536
2.7.11.22	cyclin	regulatory subunit of the CDK	666728
2.7.11.22	cyclin A	-	666862, 691801
2.7.11.22	cyclin A	cofactor of CDK2	694510, 707917
2.7.11.22	cyclin A	competes with cyclin E isoforms	665497
2.7.11.22	cyclin A	complexes with CDKA	666635
2.7.11.22	cyclin A	cyclin Acyclin-dependent enzyme. Phosphorylation of elongation factor 2 on Ser595 by the cyclin A-dependent enzyme directly stimulates phosphorylation of elongation factor 2 by elongation factor 2 kinase on Thr56	723178
2.7.11.22	cyclin A	full activation of CDK2 requires both binding of cyclin A or cyclin E and phosphorylation of residue T160 in the activation segment (also known as the T-loop) by the CDK-activating kinase	695013
2.7.11.22	cyclin A	in complex with CDK2	691302
2.7.11.22	cyclin A	is required as regulatory subunit of CDK2 in cell cycle S, M, and G1 phases	665840

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Release 2023.1 (January 2023)