EC Number   |
Cofactor |
Reference |
|---|
   2.7.1.127 | Calmodulin |
Ca2+/calmodulin-dependent, 10fold stimulation, reversed upon chelation of Ca2+ by EGTA |
640734 |
| 2.7.1.127 | Calmodulin |
effects of Ca2+/calmodulin on enzyme activity |
640743 |
| 2.7.1.127 | Calmodulin |
isoform C is strongly activated by Ca2+/calmodulin in a substrate concentration-dependent manner |
640761 |
| 2.7.1.127 | Calmodulin |
isoforms A and B are differentially regulated by Ca2+/calmodulin, isoform A: 2.5fold stimulation, isoform B: 20fold stimulation |
640759 |
| 2.7.1.127 | Calmodulin |
maximal at 50 nM calmodulin, reversed by EGTA, interaction between the Ca2+-calmodulin complex and enzyme |
640750 |
| 2.7.1.127 | Calmodulin |
maximally 5fold stimulation by 0.01 mM Ca2+/calmodulin, reversible |
640739 |
| 2.7.1.127 | Calmodulin |
mechanism of activation |
640734, 640741 |
| 2.7.1.127 | Calmodulin |
mediates activation by Ca2+ |
640754 |
| 2.7.1.127 | Calmodulin |
phosphorylation of isoenzyme B has no effect on the sensitivity to the Ca2+/calmodulin complex |
640758 |
| 2.7.1.127 | Calmodulin |
phosphorylation of Thr-311 of isoenzyme A by CaM kinase II results in a 25fold increase in sensitivity to the Ca2+/calmodulin complex, maximally 2-2.5fold stimulation by the Ca2+/calmodulin complex |
640756 |
