EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.2.64 | guanine34 in tRNA + queuine |
- |
Drosophila melanogaster |
queuine34 in tRNA + guanine |
- |
? |
2.4.2.64 | guanine34 in tRNA + queuine |
the enzyme replaces a guanine in the anticodon of tRNAs for Asn, Asp, His, and Tyr. In the absence of queuine, this enzyme catalyzes an exchange between free guanine with guanine |
Drosophila melanogaster |
queuine34 in tRNA + guanine |
- |
? |
2.4.2.64 | guanine34 in tRNA + queuine |
- |
Escherichia coli |
queuine34 in tRNA + guanine |
- |
r |
2.4.2.64 | more |
- |
Escherichia coli |
? |
- |
? |
2.4.2.64 | more |
key enzyme involved in the incorporation of the modified base queuine into tRNA |
Escherichia coli |
? |
- |
? |
2.4.2.64 | tRNAqueuine + guanine |
- |
Escherichia coli |
tRNAguanine + queuine |
- |
? |
2.4.2.64 | tRNAqueuine + hypoxanthine |
- |
Escherichia coli |
tRNAhypoxanthine + queuine |
- |
? |
2.4.2.64 | tRNAqueuine + xanthine |
- |
Escherichia coli |
tRNAxanthine + queuine |
- |
? |
2.4.2.64 | guanine34 in tRNA + 7-aminomethyl-7-carbaguanine |
very low activity with wild-type enzyme. The mutant enzyme V161C exhibits a significant improvement in preQ1 (7-aminomethyl-7-deazaguanine) recognition |
Homo sapiens |
7-aminomethyl-7-carbaguanine34 in tRNA + guanine |
- |
? |
2.4.2.64 | guanine34 in tRNA + queuine |
- |
Homo sapiens |
queuine34 in tRNA + guanine |
- |
r |