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Information on EC 2.4.2.64 - tRNA-guanosine34 queuine transglycosylase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.64 tRNA-guanosine34 queuine transglycosylase
IUBMB Comments
Certain prokaryotic and eukaryotic tRNAs contain the modified base queuine at position 34. In eukaryotes and a small number of prokaryotes queuine is salvaged and incorporated into tRNA directly via a base-exchange reaction, replacing guanine. cf. EC 2.4.2.29, tRNA-guanosine34 preQ1 transglycosylase.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
guanine,queuine-tRNA transglycosylase, QTRT1, QTRT2, QTRTD1, queuine tRNA-ribosyltransferase 1, queuine tRNA-ribosyltransferase domain-containing 1, TGT, tRNA-guanine transglycosidase, tRNA-guanine transglycosylase, tRNA-guanine transglycosylases, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
guanine34 in tRNA + queuine = queuine34 in tRNA + guanine
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