EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.18 | 15-phenylheme + electron donor + O2 |
- |
Homo sapiens |
10-phenylbiliverdin IXalpha + Fe2+ + CO + oxidized eletron donor + H2O |
- |
? |
1.14.14.18 | 5-phenylheme + electron donor + O2 |
- |
Homo sapiens |
biliverdin IXalpha + Fe2+ + CO + oxidized eletron donor + H2O + benzoic acid |
- |
? |
1.14.14.18 | alpha-meso-formylmesoheme + NADPH |
exclusively oxidized at a non-formyl substituted meso-carbon |
Homo sapiens |
? + NADP+ |
- |
? |
1.14.14.18 | alpha-meso-hydroxyhemin IX + reduced acceptor + O2 |
- |
Rattus norvegicus |
verdoheme IXalpha + CO + acceptor + H2O |
- |
? |
1.14.14.18 | beta-meso-hydroxyhemin IX + reduced acceptor + O2 |
- |
Rattus norvegicus |
verdoheme IXbeta + CO + acceptor + H2O |
- |
? |
1.14.14.18 | delta-meso-hydroxyhemin IX + reduced acceptor + O2 |
- |
Rattus norvegicus |
verdoheme IXdelta + CO + acceptor + H2O |
- |
? |
1.14.14.18 | gamma-CH-Fe(cor) + 3 AH2 + 3 O2 |
the regioisomeric iron corrole is an artificial, not-natural substrate, the enzymatic cleavage happens selectively at the unexpected bipyrrolic position and yields a biomimetic biliverdin-like product. The enzymatic corrole ring opening is selective for this corrole regioisomer and for plant-type heme oxygenase, mechanism, overview |
Arabidopsis thaliana |
? |
- |
? |
1.14.14.18 | gamma-CH-Fe(cor) + 3 AH2 + 3 O2 |
the regioisomeric iron corrole is an artificial, not-natural substrate, the enzymatic cleavage happens selectively at the unexpected bipyrrolic position and yields a biomimetic biliverdin-like product. The enzymatic corrole ring opening is selective for this corrole regioisomer and for plant-type heme oxygenase, mechanism, overview |
Synechocystis sp. |
? |
- |
? |
1.14.14.18 | gamma-meso-hydroxyhemin IX + reduced acceptor + O2 |
- |
Rattus norvegicus |
verdoheme IXgamma + CO + acceptor + H2O |
- |
? |
1.14.14.18 | heme + 2 NADH + 2 H+ + 2 O2 |
NADH-dependent heme degradation system may have a biological role in regulating the concentration of respiratory hemoproteins and the disposition of the aberrant forms of the mitochondrial hemoproteins |
Bos taurus |
biliverdin + Fe2+ + CO + 2 NAD+ + H2O |
- |
? |