EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.4.14 | more |
the enzyme shows enantioselectivity, acceptor-binding site structure of human UMP-CMP kinase in the closed form or in ligand-bound forms, overview |
Homo sapiens |
? |
- |
? |
2.7.4.14 | more |
hyperensitivity and resistance against anti-cancer drugs in the different cervical tumour cell lines, effects of changes on UMP/CMPK1 expression on CTP and UTP synthesis , overview |
Homo sapiens |
? |
- |
? |
2.7.4.14 | more |
CMP and UMP are the preferred substrates for purified CMPK, and it has lower affinity to dCMP and dUMP |
Homo sapiens |
? |
- |
? |
2.7.4.14 | more |
mutants P64T/R134M and R134M show no activity with all substrates |
Homo sapiens |
? |
- |
? |
2.7.4.14 | TTP + CMP |
- |
Homo sapiens |
TDP + CDP |
- |
? |
2.7.4.14 | TTP + dCMP |
- |
Homo sapiens |
TDP + dCMP |
- |
? |
2.7.4.14 | TTP + UMP |
- |
Homo sapiens |
TDP + UDP |
- |
? |
2.7.4.14 | UTP + CMP |
- |
Rattus norvegicus |
UDP + CDP |
- |
? |
2.7.4.14 | XTP + CMP |
- |
Rattus norvegicus |
XDP + CDP |
- |
? |
2.7.4.14 | ATP + gemcitabine phosphate |
activity of CMPK |
Homo sapiens |
ADP + gemcitabine diphosphate |
i.e. 2',2'-difluorodeoxycytidine 5'-diphosphate |
? |