EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
- |
Canis lupus familiaris |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
- |
Xenopus laevis |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
- |
Caenorhabditis elegans |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
p110delta controls a critical checkpoint in peripheral T cell differentiation and clonal expansion |
Mus musculus |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
PI3Kp110delta is the main source of production of 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate following antigen recognition by B cells, T cells and mast cells |
Mus musculus |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
catalyzed by class I enzyme, overview. PI3K is part of the plasma membrane E-cadherin signaling complex |
Canis lupus familiaris |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
- |
Mus musculus |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
- |
Homo sapiens |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate |
- |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
- |
Mus musculus |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate |
phosphatidylinositol-3,4,5-triphosphate is a major product of active PI3K, and recruits Akt/PKB to the plasma membrane and the phosphorylation of Akt occurs |
? |
2.7.1.153 | ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate |
catalyzed by class I enzyme, overview. PI3K is part of the plasma membrane E-cadherin signaling complex |
Homo sapiens |
ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate |
- |
? |