EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.18.5 | more |
enzyme is a bifunctional sphingolipid DELTA4-desaturase/C4-hydroxylase, with the desaturase activity being one order of magnitude higher than the hydroxylase activity |
Leishmania major |
? |
- |
? |
1.14.18.5 | N-acetylsphinganine + NADPH + H+ + O2 |
- |
Zea mays |
N-acetyl-4-hydroxysphinganine + NADP+ + H2O |
- |
? |
1.14.18.5 | N-hexanoylsphinganine + NADPH + H+ + O2 |
- |
Zea mays |
N-hexanoyl-4-hydroxysphinganine + NADP+ + H2O |
- |
? |
1.14.18.5 | N-octanoyl-D-erythro-dihydrosphingosine + reduced acceptor + H+ + O2 |
- |
Homo sapiens |
? |
- |
? |
1.14.18.5 | N-octanoylsphinganine + NADPH + H+ + O2 |
- |
Zea mays |
N-octanoyl-4-hydroxysphinganine + NADP+ + H2O |
- |
? |
1.14.18.5 | sphinganine + reduced acceptor + H+ + O2 |
- |
Wickerhamomyces ciferrii |
phytosphinganine + acceptor + H2O |
- |
? |
1.14.18.5 | sphinganine + reduced acceptor + H+ + O2 |
- |
Arabidopsis thaliana |
phytosphinganine + acceptor + H2O |
- |
? |
1.14.18.5 | sphinganine ceramide + 2 ferrocytochrome b5 + O2 + 2 H+ |
- |
Mus musculus |
4-hydroxysphinganine ceramide + 2 ferricytochrome b5 + H2O |
plus (E)-sphing-4-enine ceramide, the (E)-sphing-4-enine/4-hydroxysphinganine ratio is 2.5:1 |
? |
1.14.18.5 | sphingosine + reduced acceptor + H+ + O2 |
- |
Homo sapiens |
phytosphingosine + acceptor + H2O |
- |
? |