EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   6.5.1.3 | more |
the enzyme is unreactive with a 5'-32P-labeled single-strand 18-mer pDNA substrate |
Naegleria gruberi |
? |
- |
? |
| 6.5.1.3 | more |
the enzyme seals nicked 3'-OH/5'-PO4 duplexes in which the 3'-OH strand is RNA. The enzyme entails reaction with ATP to form a covalent enzyme-AMP intermediate, transfer of AMP to the nick 5'-PO4, and attack of the RNA 3'-OH on the adenylylated nick to form a 3'-5' phosphodiester |
Naegleria gruberi |
? |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
the TS2126 RNA ligase catalyzes both inter- and intra-molecular single-stranded DNA ligation to more than 50% completion in not more than a few hours at an elevated temperature, although favoring intramolecular ligation on RNA and single-stranded DNA substrates |
Phage TS2126 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m |
- |
Pyrococcus horikoshii |
(ribonucleotide)n+m + AMP + diphosphate |
- |
? |
| 6.5.1.3 | ATP + [RNA ligase]-L-lysine |
- |
Pyrococcus horikoshii |
[RNA ligase]-N6-(5'-adenylyl)-L-lysine + diphosphate |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
- |
Rhodothermus phage RM378 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
Trl1 executes the end-healing and end-sealing steps of tRNA splicing, requires a 2'-PO4 end for tRNA splicing in vivo |
Saccharomyces cerevisiae |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
- |
synthetic construct |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
ligates two substrate RNAs, promoting the attack of the 3'-hydroxyl of one substrate upon the 5'-triphosphate of the other substrate with release of diphosphate, reverse of ligation has been detected, but very inefficient, not saturable by soluble amounts of diphosphate |
synthetic construct |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (RNA)n |
- |
synthetic construct |
? |
- |
? |
