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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3more the group I intron from cyanobacterium Anabaena sp. catalyzes phosphodiester bond formation using a triphosphate on the 5'-terminal nucleotide, much like protein polymerases and engineered ribozymes. In the process, this ribozyme forms a unique circular RNA that incorporates the exogenous guanosine cofactor added during self-splicing Anabaena sp. ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3ATP + (ribonucleotide)n + (ribonucleotide)m - Branchiostoma floridae AMP + diphosphate + (ribonucleotide)n+m - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3more the RNA ligase has a a strict requirement for RNA substrates with a 2'-phosphate terminus for the ligation of RNAs with 5'-phosphate and 3'-hydroxyl ends. RNA ligase forms a 2'-phosphomonoester-3',5'-phosphodiester junction Branchiostoma floridae ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3ATP + (ribonucleotide)n + (ribonucleotide)m DraRnl seals 3'-OH/5'-PO4 RNA nicks in either a duplex RNA or an RNA:DNA hybrid, but it cannot seal 3'-OH/5'-PO4 DNA nicks Deinococcus radiodurans AMP + diphosphate + (ribonucleotide)n+m - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m - Diplonema papillatum (ribonucleotide)n+m + AMP + diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3ATP + (ribonucleotide)n + (ribonucleotide)m the L1 ligase is regioselective for formation of the biologically relevant 5' to 3' phosphodiester bond rather than a 5' to 2' bond Enterobacteria phage L1 AMP + diphosphate + (ribonucleotide)n+m - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3ATP + (ribonucleotide)n + (ribonucleotide)m T4 RNA ligase 1 can efficiently adenylate DNA oligos with 5' phosphate and 3' blocking group Escherichia coli AMP + diphosphate + (ribonucleotide)n+m - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3more RtcA is able of cyclizing a 2'-phosphate RNA end in high yield. The rate of 2'-phosphate cyclization by RtcA is five orders of magnitude slower than 3'-phosphate cyclization, notwithstanding that RtcA binds with similar affinity to RNA3'p and RNA2'p substrates Escherichia coli ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3ATP + (ribonucleotide)n + (ribonucleotide)m - Homo sapiens AMP + diphosphate + (ribonucleotide)n+m - ?
Display the word mapDisplay the reaction diagram Show all sequences 6.5.1.3dATP + (ribonucleotide)n + (ribonucleotide)m - Homo sapiens dAMP + phosphate + (ribonucleotide)n+m - ?
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