EC Number   |
Source Tissue |
Reference |
|---|
    2.6.1.42 | aorta |
endothelial cells |
640023 |
| 2.6.1.42 | AS-30D cell |
hepatoma cell, expresses only mitochondrial isoform |
662753 |
| 2.6.1.42 | astrocyte |
- |
640019, 640025 |
| 2.6.1.42 | basal ganglion |
- |
675509 |
| 2.6.1.42 | blood |
- |
640034, 640037 |
| 2.6.1.42 | brain |
- |
639997, 640009, 640019, 640025, 640028, 640031, 640037, 640039, 672589, 672847, 673846, 675509, 705527, 723026, 758607, 758657 |
| 2.6.1.42 | brain |
in human brain, BCATc is solely expressed in glutamatergic and GABAergic neurons in all brain regions examined. In the hippocampal and temporal region of the brain, intense staining of BCATc is reported in the neuronal cell bodies indicating that the role of BCATc is to contribute to the glutamate pool rather than excitation. A role in neurotransmitter release during excitation is also proposed as BCATc is localised along the axons. Isozyme BCAT1 reguation in the brain, overview |
758657 |
| 2.6.1.42 | brain stem |
- |
675509 |
| 2.6.1.42 | breast cancer cell |
- |
758728 |
| 2.6.1.42 | breast cancer cell |
BCATc and BCATm are increased in breast cancer |
758657 |
