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EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B29malfunction inhibition of CAPN9 expression in MCF7/CEACAM1-4S cells by RNAi or by calpeptin or PD150606 inhibits lumen formation 708419
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B29physiological function calpain-9 may play a role in breast cance, low expression is associated with poorer patient clinical outcome following endocrine therapy, but no associations are observed between calpain-9 expression and clinicopathological variables 731549
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B29physiological function TGFbeta-induced mesenchymal transition of a murine breast epithelial cell line is dependent on induction of expression of calpain 9. Mice lacking functional CAPN9 are viable and fertile but show overt protection from bleomycin-induced lung fibrosis, carbon tetrachloride-induced liver fibrosis, and angiotensin II-induced cardiac fibrosis and dysfunction 755531
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