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Literature summary for 3.4.22.B29 extracted from
- Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells (2010), Exp. Cell Res., 316, 638-648.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| calpeptin | pan-calpain inhibitor | Homo sapiens |  |
| PD150606 | pan-calpain inhibitor | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| breast epithelial cell | - |
Homo sapiens | - |
| MCF-7 cell | - |
Homo sapiens | - |
| MCF-7 cell | transfected with CEACAM1-4S (carcinoembryonic antigen-related cell adhesion molecule 1), a type I membrane protein with a short (12-amino acid) cytoplasmic tail | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calpain-9 | - |
Homo sapiens |
| CAPN9 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | inhibition of CAPN9 expression in MCF7/CEACAM1-4S cells by RNAi or by calpeptin or PD150606 inhibits lumen formation | Homo sapiens |
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