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Literature summary for 3.4.22.B29 extracted from

  • Kim, D.H.; Beckett, J.D.; Nagpal, V.; Seman-Senderos, M.A.; Gould, R.A.; Creamer, T.J.; MacFarlane, E.G.; Chen, Y.; Bedja, D.; Butcher, J.T.; Mitzner, W.; Rouf, R.; Hata, S.; Warren, D.S.; Dietz, H.C.
    Calpain 9 as a therapeutic target in TGFbeta-induced mesenchymal transition and fibrosis (2019), Sci. Transl. Med., 11, eaau2814 .
    View publication on PubMed
Search for more literature for 3.4.22.B29

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
MDCK cell
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 Mus musculus
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NMuMg cell
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 Mus musculus
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General Information

General Information Comment Organism
physiological function TGFbeta-induced mesenchymal transition of a murine breast epithelial cell line is dependent on induction of expression of calpain 9. Mice lacking functional CAPN9 are viable and fertile but show overt protection from bleomycin-induced lung fibrosis, carbon tetrachloride-induced liver fibrosis, and angiotensin II-induced cardiac fibrosis and dysfunction Mus musculus