EC Number |
General Information |
Reference |
---|
3.1.1.59 | physiological function |
Bmcce-5 is strongly expressed in Malpighian tubules and the gut, it might function in digestion or xenobiotic metabolism |
715173 |
3.1.1.59 | physiological function |
BmJHE, a juvenile hormone-selective esterase, JHE, is important for juvenile hormone titer regulation in the silkworm Bombyx mori |
715173 |
3.1.1.59 | physiological function |
JHEs are required for the degradation of juvenile hormones in insects |
715184 |
3.1.1.59 | physiological function |
JHE is the enzyme primarily performing juvenile hormone degradation in Apis mellifera, while the JH epoxide hydrolase, EC 3.3.2.9, plays a negligible role |
715819 |
3.1.1.59 | malfunction |
silencing of the enzyme affects expression of the other developmental genes without a specific phenotype, e.g. mRNA accumulation of heat shock protein 70, SnHsp70, is increased while the heat shock cognate 70, SnHsc70, and ecdysone receptor, SnEcR, mRNA accumulation is decreased |
730748 |
3.1.1.59 | physiological function |
the enzyme plays a critical role in regulating larval to adult transition in insects and other arthropods. It is following the ecdysteroid titer of Sesamia nonagrioides in contrast to other conventional JHE genes of several insects. The enzyme is implicated in larval-larval molt of Sesamia nonagrioides larvae. The enzyme is implicated in the ecdysteroid instead of the juvenile hormone signalling by interfering with the molting process |
730748 |
3.1.1.59 | malfunction |
upon RNAi-mediated silencing of the methyl farnesoate epoxidase gene mfe encoding the enzyme that catalyzes methyl farnesoate-to-juvenile hormone conversion, the juvenile hormone titer is decreased, juvenile hormone titer regulation in adult honey bees depends on this final juvenile hormone biosynthesis step, overview |
730778 |
3.1.1.59 | physiological function |
juvenile hormone controls key events in the honey bee life cycle, the juvenile hormone-degrading enzyme is of importance in regulating larval juvenile hormone titers and caste development, as well as age polyethism, expression of 24 genes involved in the juvenile hormone biosynthetic pathway in the corpora allata-corpora cardiaca, overview |
730778 |
3.1.1.59 | physiological function |
penultimate (4th) instar larvae infected with nucleopolyhedroviruses AdhoNPV or AdorNPV show a marked decrease in JHE activity. The mean survival time is 9.7 and 8.2 days, respectively. The larvae molt once but do not pupate |
751263 |
3.1.1.59 | physiological function |
knockdown of expression by RNAi reduces juvenile hormone esterase activity and interrupts pupal development with a significant increase of larval period |
751264 |